JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) gamma-8, with a pIC50 of 9.7 for GluA1/gamma-8. Exhibits time- and dose-dependent AMPAR/gamma-8 receptor occupancy in mouse hippoc
Molecular Weight:
443.47
Purity:
99.06
CAS Number:
[2035814-50-5]
Formula:
C25H22FN5O2
Target:
iGluR
Application Notes:
Reference compound
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