Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
Molecular Weight:
591.1
Purity:
95
CAS Number:
[1639351-92-0]
Formula:
C28H39ClN6O6
Target:
ADC Linker
Application Notes:
ADC Related
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