MMG-11 is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].
Molecular Weight:
306.27
Purity:
99.11
CAS Number:
[313254-94-3]
Formula:
C15H14O7
Target:
Toll-like Receptor (TLR)
Application Notes:
Reference compound
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