GGTI-286 TFA, a potent and cell-permeable GGTase I inhibitor, is 25-fold more potent (IC50=2 µM) than the corresponding methyl ester of FTI-276 (HY-15873A). GGTI-286 TFA selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH
Molecular Weight:
543.6
Formula:
C25H32F3N3O5S
Target:
Others
Application Notes:
Reference compound
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