SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 µM for ST-hSK. SKI-I also inhibits hERK2 (IC50=11 µM). SKI-I induces apoptosis in tumor cell lines[1][2].
Molecular Weight:
406.44
Purity:
99.14
CAS Number:
[306301-68-8]
Formula:
C25H18N4O2
Target:
Apoptosis,SphK
Application Notes:
Reference compound
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