4-PQBH is a potent Nur77 binder (KD=1.17 µM). 4-PQBH extensively induces caspase-independent cytoplasmic vacuolization and paraptosis through Nur77-mediated ER stress and autophagy. 4-PQBH can be used for cancer research[1].
Molecular Weight:
367.40
Purity:
99.08
CAS Number:
[2243355-51-1]
Formula:
C22H17N5O
Target:
Nuclear Hormone Receptor 4A/NR4A,Paraptosis
Application Notes:
Reference compound
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