PDE4-IN-6 is a potent, safe and moderately selective PDE4 inhibitor with IC50s of 0.125 and 0.43 µM for PDE4B and PDE4D, respectively. PDE4-IN-6 can downregulate the expression level of TNF-alpha and IL-6. PDE4-IN-6 has potent immunomodulatory activity there
Molecular Weight:
465.49
Formula:
C25H20FNO5S
Target:
Phosphodiesterase (PDE)
Application Notes:
Reference compound
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