JH295 is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 inhibits cellular Nek2 via alkylation of Cys22. JH295 is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb
Molecular Weight:
320.35
Purity:
98.99
CAS Number:
[1311143-71-1]
Formula:
C18H16N4O2
Target:
Others
Application Notes:
Reference compound
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