JH295 hydrate is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 hydrate inhibits cellular Nek2 via alkylation of Cys22. JH295 hydrate is inactive against the mitotic kinases, Cdk1, Aurora B or Pl
Molecular Weight:
338.36
Purity:
99
CAS Number:
[2714087-26-8]
Formula:
C18H18N4O3
Target:
Others
Application Notes:
Reference compound
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