YKL-1-116 is a selective and covalent inhibitor of Cdk7. YKL-1-116 does not target Cdk9, Cdk12, or Cdk13. YKL-1-116 is more potent than THZ1 (HY-80013) toward both Cdk7WT and Cdk7as, although Cdk7as is relatively resistant to this compound as well[1].
Molecular Weight:
606.72
CAS Number:
[1957202-71-9]
Formula:
C34H38N8O3
Target:
CDK
Application Notes:
Reference compound
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