JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3
Molecular Weight:
617.18
Purity:
99.78
CAS Number:
[2260886-64-2]
Formula:
C33H41ClN8O2
Target:
EGFR
Application Notes:
Reference compound
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