AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells[1].
Molecular Weight:
237.30
CAS Number:
[510721-85-4]
Formula:
C15H15N3
Target:
DNA/RNA Synthesis
Application Notes:
Reference compound
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