MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis
Molecular Weight:
370.83
Purity:
99.62
CAS Number:
[1672684-68-2]
Formula:
C20H19ClN2O3
Target:
Epigenetic Reader Domain
Application Notes:
Reference compound
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