DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation[1
Molecular Weight:
282.29
Purity:
99.40
CAS Number:
[187585-11-1]
Formula:
C16H14N2O3
Target:
Apoptosis,Proteasome,Ribosomal S6 Kinase (RSK)
Application Notes:
Reference compound
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