ND-2158 is a competitive IRAK4 inhibitor, with the Ki of 1.3 nM. ND-2158 suppresses LPS-induced TNF production in human white blood cells, alleviated collagen-induced arthritis, and blocked gout formation in mouse models. ND-2158 has antitumor activity i
Molecular Weight:
446.56
CAS Number:
[1388896-07-8]
Formula:
C22H30N4O4S
Target:
IRAK
Application Notes:
Reference compound
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