NBC19 is an NLRP3 inflammasome inhibitor with an IC50 of 60 nM in differentiated THP1 cells. NBC19 inhibits nigericin- and ATP-induced IL-1beta release with IC50s of 80 nM and 850 nM, respectively[1].
Molecular Weight:
491.65
CAS Number:
[2068818-75-5]
Formula:
C24H26BCl3N2O2
Target:
NOD-like Receptor (NLR)
Application Notes:
Reference compound
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