Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the alpha5-GABAAR, with an IC50 of 585 nM for alpha5beta2gamma2 and a Ki of 66 nM for alpha5beta3gamma2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro
Molecular Weight:
365.38
Purity:
98.29
CAS Number:
[1398496-82-6]
Formula:
C19H12FN3O2S
Target:
GABA Receptor
Application Notes:
Reference compound
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