Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice[1].
Molecular Weight:
561.98
Purity:
99.11
CAS Number:
[1673568-73-4]
Formula:
C27H27ClF3N5O3
Target:
5-HT Receptor,Tryptophan Hydroxylase
Application Notes:
Reference compound
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