BTX161, a Thalidomide analog, is a potent CKIalpha degrader. BTX161 mediates degradation of CKIalpha better than Lenalidomide in human AML cells and activates DNA damage response (DDR) and p53, while stabilizing the p53 antagonist MDM2[1].
Molecular Weight:
272.30
Purity:
98.58
CAS Number:
[2052301-24-1]
Formula:
C15H16N2O3
Target:
Casein Kinase
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted