KG-548 is an ARNT/TACC3 disruptor and a HIF-1alpha inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as
Molecular Weight:
282.15
Purity:
99.92
CAS Number:
[175205-09-1]
Formula:
C9H4F6N4
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
Reference compound
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