APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 µM, 0.57 µM, and 0.63 µM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury[1].
Molecular Weight:
279.34
Purity:
98.11
CAS Number:
[1270084-92-8]
Formula:
C17H17N3O
Target:
NADPH Oxidase
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted