EP009 is a JAK3 inhibitor that selectively inhibits IL-2-mediated JAK3 tyrosine phosphorylation (IC50=10-20 µM in Kit225 cells) without affecting IL-3-induced JAK2 phosphorylation (up to 50 µM in BaF/3 cells). EP009 significantly reduced Kit225 cell viab
Molecular Weight:
224.34
CAS Number:
[1462951-30-9]
Formula:
C14H24O2
Target:
JAK
Application Notes:
Reference compound
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