JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 µM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 µM)[1].JR-AB2-011 decreases the phosphorylation level of Akt, decreases MMP2 activity, thereby red
Molecular Weight:
398.28
Purity:
99.16
CAS Number:
[2411853-34-2]
Formula:
C17H14Cl2FN3OS
Target:
mTOR
Application Notes:
Reference compound
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