PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also en
Molecular Weight:
328.29
Purity:
98.88
CAS Number:
[1462249-75-7]
Formula:
C18H11F3N2O
Target:
Apoptosis,Autophagy
Application Notes:
Reference compound
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