MK181 is an aldose reductase (AR) inhibitor with IC50s of 0.71 µM and 4.5 µM for aldose reductase and AKR1B10, respectively. MK181 can bind into the external loop A subpocket of AKR1B10[1].
Molecular Weight:
398.64
CAS Number:
[314297-32-0]
Formula:
C16H13BrClNO4
Target:
Aldose Reductase
Application Notes:
Reference compound
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