PET-16 is a selective HSP70 inhibitor that binds to an allosteric pocket of the substrate-binding domain. PET-16 inhibits the ability of HSP70 to cycle between ATP-bound and ADP-bound states. PET-16 induces apoptosis in multiple myeloma[1].
Molecular Weight:
443.31
CAS Number:
[34387-64-9]
Formula:
C26H20BrP
Target:
Apoptosis,HSP
Application Notes:
Reference compound
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