JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON, HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells and experimental cerebral malaria (ECM) resulting in a net decrease of
Molecular Weight:
312.36
Purity:
98
CAS Number:
[1998725-11-3]
Formula:
C14H24N4O4
Target:
Glutaminase
Application Notes:
Reference compound
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