T-448 is a specific, orally active and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons[1].
Molecular Weight:
386.50
Purity:
98.86
CAS Number:
[1597426-53-3]
Formula:
C17H20N4OS.1/2C4H4O4
Target:
Histone Demethylase
Application Notes:
Reference compound
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