HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. HOIPIN-8 is a HOIPIN-1 derivative with enhanced the potency by 255-fold in the petit-LUBAC inhibition, and 10-fold and 4-fold in the LUBAC- and TNF-alpha
Molecular Weight:
456.38
Purity:
99.89
Formula:
C23H15F2N4NaO3
Target:
E1/E2/E3 Enzyme
Application Notes:
Reference compound
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