Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and
Molecular Weight:
560.67
Purity:
99.01
CAS Number:
[950769-58-1]
Formula:
C29H32N6O4S
Target:
Apoptosis,FLT3,Ligands for Target Protein for PROTAC
Application Notes:
Reference compound
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