(E)-SIS3 is a potent and selective inhibitor of Smad3 with an IC50 of 3 µM for Smad3 phosphorylation. (E)-SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-beta1[1].
Molecular Weight:
489.99
Purity:
98.71
CAS Number:
[521984-48-5]
Formula:
C28H28ClN3O3
Target:
TGF-beta/Smad
Application Notes:
Reference compound
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