Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. Adagrasib covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP
Molecular Weight:
604.12
Purity:
99.93
CAS Number:
[2326521-71-3]
Formula:
C32H35ClFN7O2
Target:
Ras
Application Notes:
Reference compound
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