BMS-1166-N-piperidine-COOH, the BMS-1166-based moiety, binds to E3 ligase ligand via a linker to form PROTAC PD-1/PD-L1 degrader-1 (HY-131183) to degrade PD-1/PD-L1[1]. BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-116
Molecular Weight:
639.14
Purity:
97.26
CAS Number:
[2447066-00-2]
Formula:
C37H35ClN2O6
Target:
Ligands for Target Protein for PROTAC
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted