Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 µM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell apoptosis. Anti-hepatoma activity[
Molecular Weight:
495.6
Purity:
98.61
CAS Number:
[2469975-55-9]
Formula:
C28H25N5O2S
Target:
Apoptosis,Nuclear Hormone Receptor 4A/NR4A
Application Notes:
Reference compound
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