TPBM is a potent estrogen receptor alpha (ERalpha) inhibitor with an IC50 value of 9 µM for 17beta-estradiol (E2)-ERalpha. TPBM reduces E2ERalpha recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERalpha-positive cancer cells (IC50=5
Molecular Weight:
316.38
Purity:
98.51
CAS Number:
[6466-43-9]
Formula:
C15H16N4O2S
Target:
Estrogen Receptor/ERR
Application Notes:
Reference compound
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