LEO 39652 is a dual-soft PDE4 inhibitor with IC50s of 1.2 nM, 1.2 nM, 3.0 nM and 3.8 nM for PDE4A, PDE4B, PDE4C and PDE4D, respectively. LEO 39652 also inhibits TNF-alpha with an IC50 value of 6.0 nM. LEO 39652 is used for topical research of Atopic dermatit
Molecular Weight:
421.45
Purity:
99.51
CAS Number:
[1445656-91-6]
Formula:
C23H23N3O5
Target:
Phosphodiesterase (PDE)
Application Notes:
Reference compound
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