PDE5-IN-3 (compound 11j) is a potent PDE5 inhibitor with an IC50 of 1.57 nM. PDE5-IN-3 shows moderate EGFR inhibition with IC50 of 5.827 µM. PDE5-IN-3 significantly inhibits the Wnt/beta-catenin pathway (IC50=1286.96 ng/mL). PDE5-IN-3 induces the intrinsic
Molecular Weight:
448.27
CAS Number:
[2538149-57-2]
Formula:
C21H14BrN5O2
Target:
Apoptosis,EGFR,Phosphodiesterase (PDE),Wnt
Application Notes:
Reference compound
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