AR-42 (HDAC-42, OSU-HDAC42) is a potent, orally bioavailable pan-HDAC inhibitor (IC50=16 nM). AR-42 induces growth inhibition, cell-cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 promotes hyperacetylation of H3, H4, and alpha-tubulin, and
Molecular Weight:
312.36
Purity:
98.69
CAS Number:
[935881-37-1]
Formula:
C18H20N2O3
Target:
Apoptosis,Autophagy,HDAC
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted