BS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer
Molecular Weight:
380.53
Purity:
98.1
CAS Number:
[1092443-52-1]
Formula:
C22H32N6
Target:
Apoptosis,CDK
Application Notes:
Reference compound
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