(S)-Sunvozertinib ((S)-DZD9008), the S-enantiomer of Sunvozertinib, shows inhibitory activity against EGFR exon 20 NPH and ASV insertions, EGFR L858R/T790M mutation and Her2 exon20 YVMA insertion (IC50=51.2 nM, 51.9 nM, 1 nM, and 21.2 nM, respectively).
Molecular Weight:
584.08
Purity:
99.14
CAS Number:
[2370013-49-1]
Formula:
C29H35ClFN7O3
Target:
Btk,EGFR
Application Notes:
Reference compound
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