Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1].
Molecular Weight:
428.84
Purity:
99.10
CAS Number:
[1402086-20-7]
Formula:
C21H18ClFN4O3
Target:
Autophagy,EGFR
Application Notes:
Reference compound
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