G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity[1].
Molecular Weight:
379.24
Purity:
98.11
CAS Number:
[2369751-07-3]
Formula:
C17H16Cl2N4O2
Target:
Cyclic GMP-AMP Synthase
Application Notes:
Reference compound
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