Capmatinib (INC280, INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor (IC50=0.13 nM). Capmatinib can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1,
Molecular Weight:
412.42
Purity:
99.92
CAS Number:
[1029712-80-8]
Formula:
C23H17FN6O
Target:
Apoptosis,c-Met/HGFR
Application Notes:
Reference compound
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