TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells.
Molecular Weight:
531.13
Purity:
99.73
CAS Number:
[229005-80-5]
Formula:
C33H39ClN2O2
Target:
CCR,CXCR,HIV
Application Notes:
Reference compound
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