AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent
Molecular Weight:
431.41
Purity:
99.98
CAS Number:
[1227163-84-9]
Formula:
C24H16F3N5
Target:
Beta-secretase
Application Notes:
Reference compound
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