AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks, with Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kalpha, beta, delta and gamma, respectively. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease. AMG 511 exhi
Molecular Weight:
517.58
Purity:
99.38
CAS Number:
[1253573-53-3]
Formula:
C22H28FN9O3S
Target:
PI3K
Application Notes:
Reference compound
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