Enpatoran (M5049) hydrochloride is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran hydrochloride is inactive against TLR3, TLR4 and TLR9. Enpatoran hydrochloride can block molec
Molecular Weight:
356.77
Purity:
99.33
CAS Number:
[2101945-93-9]
Formula:
C16H16ClF3N4
Target:
Toll-like Receptor (TLR)
Application Notes:
Reference compound
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