PF-5274857 is a potent, selective, orally active and brain-penetrant antagonist of Smo, with an IC50 of 5.8 nM and Ki of 4.6 nM. PF-5274857 has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pa
Molecular Weight:
436.96
Purity:
98.89
CAS Number:
[1373615-35-0]
Formula:
C20H25ClN4O3S
Target:
Smo
Application Notes:
Reference compound
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