Aftin-5 is an inducer for Amyloid-beta 42 (Abeta42). Aftin-5 upregulates Abeta42 and downregulates Abeta38 levels in a beta-secretase- and gamma-secretase-dependent manner by altering the ultrastructure of mitochondria. Aftin-5 exhibits slightly cytotoxicity in cell SH-SY5
Molecular Weight:
354.45
CAS Number:
[1461717-05-4]
Formula:
C19H26N6O
Target:
Amyloid-beta
Application Notes:
Reference compound
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