MI-389 is a PROTAC translation termination factor GSPT1 degrader. MI-389 disrupts a target that is a shared dependency in different AML and ALL cell lines, and that MI-389 action is dependent on the CRL4CRBN E3 ligase[1].
Molecular Weight:
654.69
Purity:
99.34
CAS Number:
[2222635-92-7]
Formula:
C35H35FN6O6
Target:
PROTACs
Application Notes:
Reference compound
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